Trademark of The Dow Chemical Company (“Dow”) or an affiliated
company of Dow
Page 1 of 16
SAFETY DATA SHEET
DDP SPECIALTY ELECTRONIC MATERIALS US,
INC.
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
Print Date: 03/26/2019
DDP SPECIALTY ELECTRONIC MATERIALS US, INC. encourages and expects you to read and
understand the entire (M)SDS, as there is important information throughout the document. We expect
you to follow the precautions identified in this document unless your use conditions would necessitate
other appropriate methods or actions.
1. IDENTIFICATION
Product name: FROTH-PAK ISO INT AF HFC
Recommended use of the chemical and restrictions on use
Identified uses: For industrial use. Component(s) for the manufacture of urethane polymers. We
recommend that you use this product in a manner consistent with the listed use. If your intended use is
not consistent with the stated use, please contact your sales or technical service representative.
COMPANY IDENTIFICATION
DDP SPECIALTY ELECTR ONIC MATERIALS US,
INC.
400 ARCOLA ROAD
COLLEGEVILLE PA 19426-2914
UNITED STATES
Customer Information Number: 800-258-2436
SDSQuestion@dow.com
EMERGENCY TELEPHONE NUMBER
24-Hour Emergency Contact: 1 800 424 9300
Local Emergency Contact: 800-424-9300
2. HAZARDS IDENTIFICATION
Hazard classification
This material is hazardous under the criteria of the Federal OSHA Hazard Communication Standard
29CFR 1910.1200.
Gases under pressure – Liquefied gas
Acute toxicity – Category 4 – Inhalation
Skin irritation – Category 2
Eye irritation – Category 2B
Respiratory sensitisation – Category 1
Skin sensitisation – Category 1
Specific target organ toxicity – single exposure – Category 3
Specific target organ toxicity – repeated exposure – Category 2 – Inhalation
Label elements
Hazard pictograms
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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Signal word: DANGER!
Hazards
Contains gas under pressure; may explode if heated.
Causes skin and eye irritation.
May cause an allergic skin reaction.
Harmful if inhaled.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause respiratory irritation.
May cause damage to organs (Respiratory Tract) through prolonged or repeated exposure if inhaled.
Precautionary statements
Prevention
Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
Wash skin thoroughly after handling.
Use only outdoors or in a well-ventilated area.
Contaminated work clothing should not be allowed out of the workplace.
Wear protective gloves.
In case of inadequate ventilation wear respiratory protection.
Response
IF ON SKIN: Wash with plenty of soap and water.
IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON
CENTER/doctor if you feel unwell.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing.
If skin irritation or rash occurs: Get medical advice/ attention.
If eye irritation persists: Get medical advice/ attention.
If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
Take off contaminated clothing and wash before reuse.
Storage
Store in a well-ventilated place. Keep container tightly closed.
Store locked up.
Protect from sunlight. Store in a well-ventilated place.
Disposal
Dispose of contents/ container to an approved waste disposal plant.
Other hazards
No data available
3. COMPOSITION/INFORMATION ON INGREDIENTS
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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This product is a mixture.
Component CASRN Concentration
Diphenylmethane Diisocyanate, isomers and
homologues
9016-87-9 >= 60.0 – <= 100.0 %
4,4'-Methylenediphenyl diisocyanate 101-68-8 30.0 - <= 60.0 %
1,1,1,2-Tetrafluoroethane 811-97-2 >= 5.0 – <= 10.0 %
4. FIRST AID MEASURES
Description of first aid measures
General advice:
First Aid responders should pay attention to self-protection and use the recommended protective
clothing (chemical resistant gloves, splash protection). If potential for exposure exists refer to Section
8 for specific personal protective equipment.
Inhalation: Move person to fresh air. If not breathing, give artificial respiration; if by mouth to mouth
use rescuer protection (pocket mask, etc). If breathing is difficult, oxygen should be administered by
qualified personnel. Call a physician or transport to a medical facility.
Skin contact: Remove material from skin immediately by washing with soap and plenty of water.
Remove contaminated clothing and shoes while washing. Seek medical attention if irritation persists.
Wash clothing before reuse. An MDI skin decontamination study demonstrated that cleaning very
soon after exposure is important, and that a polyglycol-based skin cleanser or corn oil may be more
effective than soap and water. Discard items which cannot be decontaminated, including leather
articles such as shoes, belts and watchbands. Suitable emergency safety shower facility should be
available in work area.
Eye contact: Immediately flush eyes with water; remove contact lenses, if present, after the first 5
minutes, then continue flushing eyes for at least 15 minutes. Obtain medical attention without delay,
preferably from an ophthalmologist. Suitable emergency eye wash facility should be immediately
available.
Ingestion: If swallowed, seek medical attention. Do not induce vomiting unless directed to do so by
medical personnel.
Most important symptoms and effects, both acute and delayed: Aside from the information found
under Description of first aid measures (above) and Indication of immediate medical attention and
special treatment needed (below), any additional important symptoms and effects are described in
Section 11: Toxicology Information.
Indication of any immediate medical attention and special treatment needed
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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Notes to physician: Maintain adequate ventilation and oxygenation of the patient. May cause
respiratory sensitization or asthma-like symptoms. Bronchodilators, expectorants and antitussives
may be of help. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids.
Respiratory symptoms, including pulmonary edema, may be delayed. Persons receiving significant
exposure should be observed 24-48 hours for signs of respiratory distress. If you are sensitized to
diisocyanates, consult your physician regarding working with other respiratory irritants or sensitizers.
Exposure may increase "myocardial irritability". Do not administer sympathomimetic drugs such as
epinephrine unless absolutely necessary. Treatment of exposure should be directed at the control of
symptoms and the clinical condition of the patient. Excessive exposure may aggravate preexisting
asthma and other respiratory disorders (e.g. emphysema, bronchitis, reactive airways dysfunction
syndrome).
5. FIREFIGHTING MEASURES
Suitable extinguishing media: Water fog or fine spray. Dry chemical fire extinguishers. Carbon
dioxide fire extinguishers. Foam. Alcohol resistant foams (ATC type) are preferred. General purpose
synthetic foams (including AFFF) or protein foams may function, but will be less effective.
Unsuitable extinguishing media: Do not use direct water stream. May spread fire.
Special hazards arising from the substance or mixture
Hazardous combustion products: During a fire, smoke may contain the original material in addition
to combustion products of varying composition which may be toxic and/or irritating. Combustion
products may include and are not limited to: Nitrogen oxides. Isocyanates. Hydrogen cyanide.
Carbon monoxide. Carbon dioxide. Hydrogen halides. Halogenated hydrocarbons.
Unusual Fire and Explosion Hazards: Some components of this product will burn in a fire situation.
Product reacts with water. Reaction may produce heat and/or gases. This reaction may be violent.
Container may rupture from gas generation in a fire situation. Blowing agent vaporizes quickly at room
temperature. Violent steam generation or eruption may occur upon application of direct water stream
to hot liquids. Dense smoke is produced when product burns.
Advice for firefighters
Fire Fighting Procedures: Keep people away. Isolate fire and deny unnecessary entry. Stay
upwind. Keep out of low areas where gases (fumes) can accumulate. Water is not recommended, but
may be applied in large quantities as a fine spray when other extinguishing agents are not available.
Do not use direct water stream. May spread fire. Fight fire from protected location or safe distance.
Consider the use of unmanned hose holders or monitor nozzles. Immediately withdraw all personnel
from the area in case of rising sound from venting safety device or discoloration of the container.
Move container from fire area if this is possible without hazard. Use water spray to cool fire-exposed
containers and fire-affected zone until fire is out. Contain fire water run-off if possible. Fire water run-
off, if not contained, may cause environmental damage. Review the "Accidental Release Measures"
and the "Ecological Information" sections of this (M)SDS.
Special protective equipment for firefighters: Wear positive-pressure self-contained breathing
apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet, coat, trousers,
boots, and gloves). Avoid contact with this material during fire fighting operations. If contact is likely,
change to full chemical resistant fire fighting clothing with self-contained breathing apparatus. If this is
not available, wear full chemical resistant clothing with self-contained breathing apparatus and fight
fire from a remote location. For protective equipment in post-fire or non-fire clean-up situations, refer
to the relevant sections.
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures: Isolate area. Keep
unnecessary and unprotected personnel from entering the area. Refer to section 7, Handling, for
additional precautionary measures. Keep personnel out of low areas. Keep personnel out of confined
or poorly ventilated areas. Keep upwind of spill. Ventilate area of leak or spill. Confined space entry
procedures must be followed before entering the area. See Section 10 for more specific information.
Spilled material may cause a slipping hazard. Use appropriate safety equipment. For additional
information, refer to Section 8, Exposure Controls and Personal Protection.
Environmental precautions: Prevent from entering into soil, ditches, sewers, waterways and/or
groundwater. See Section 12, Ecological Information.
Methods and materials for containment and cleaning up: Contain spilled material if possible.
Absorb with materials such as: Dirt. Vermiculite. Sand. Clay. Do NOT use absorbent materials such
as: Cement powder (Note: may generate heat). Collect in suitable and properly labeled open
containers. Isolate area until gas has dispersed. Apply vapor suppression foams until spill can be
cleaned up. Knock down and dilute vapors with water fog or spray. See Section 13, Disposal
Considerations, for additional information.
7. HANDLING AND STORAGE
Precautions for safe handling: Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated contact with skin. Wash thoroughly after handling. Avoid breathing vapor. Use with
adequate ventilation. This material is hygroscopic in nature. Keep container closed. Do not enter
confined spaces unless adequately ventilated. See Section 8, EXPOSURE CONTROLS AND
PERSONAL PROTECTION.
Spills of these organic materials on hot fibrous insulations may lead to lowering of the autoignition
temperatures possibly resulting in spontaneous combustion.
Conditions for safe storage: Store in a dry place. Avoid prolonged exposure to heat and air. Protect
from atmospheric moisture. Blowing agent may migrate from product and accumulate in some storage
situations. Elevated temperatures can cause pressure buildup in closed containers due to the release
of blowing agents. Store in the following material(s): Carbon steel. Stainless steel. Polypropylene.
Polyethylene-lined container. Teflon. Glass-lined container. Aluminum. Plasite 3066 lined container.
Plasite 3070 lined container. 316 stainless steel. Do not store product contaminated with water to
prevent potential hazardous reaction. See Section 10 for more specific information.
Storage stability
Storage temperature: Storage Period:
15 - 25 C (59 - 77 F) 12 Month
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Control parameters
If exposure limits exist, they are listed below. If no exposure limits are displayed, then no values are
applicable.
Component Regulation Type of listing Value/Notation
4,4'-Methylenediphenyl
diisocyanate
Dow IHG TWA 0.005 ppm
Dow IHG STEL 0.02 ppm
ACGIH TWA 0.005 ppm
OSHA Z-1 C 0.2 mg/m3 0.02 ppm
1,1,1,2-Tetrafluoroethane US WEEL TWA 1,000 ppm
Exposure controls
Engineering controls: Use only with adequate ventilation. Local exhaust ventilation may be
necessary for some operations. Provide general and/or local exhaust ventilation to control airborne
levels below the exposure guidelines. Exhaust systems should be designed to move the air away
from the source of vapor/aerosol generation and people working at this point. The odor and irritancy
of this material are inadequate to warn of excessive exposure.
Individual protection measures
Eye/face protection: Use chemical goggles.
Skin protection
Hand protection: Use gloves chemically resistant to this material. Examples of
preferred glove barrier materials include: Butyl rubber. Chlorinated polyethylene.
Polyethylene. Ethyl vinyl alcohol laminate ("EVAL"). Examples of acceptable glove
barrier materials include: Neoprene. Nitrile/butadiene rubber ("nitrile" or "NBR").
Polyvinyl chloride ("PVC" or "vinyl"). Viton. NOTICE: The selection of a specific glove
for a particular application and duration of use in a workplace should also take into
account all relevant workplace factors such as, but not limited to: Other chemicals
which may be handled, physical requirements (cut/puncture protection, dexterity,
thermal protection), potential body reactions to glove materials, as well as the
instructions/specifications provided by the glove supplier.
Other protection: Use protective clothing chemically resistant to this material.
Selection of specific items such as face shield, boots, apron, or full body suit will
depend on the task.
Respiratory protection: Atmospheric levels should be maintained below the exposure
guideline. When atmospheric levels may exceed the exposure guideline, use an approved air-
purifying respirator equipped with an organic vapor sorbent and a particle filter. For situations
where the atmospheric levels may exceed the level for which an air-purifying respirator is
effective, use a positive-pressure air-supplying respirator (air line or self-contained breathing
apparatus). For emergency response or for situations where the atmospheric level is
unknown, use an approved positive-pressure self-contained breathing apparatus or positive-
pressure air line with auxiliary self-contained air supply.
The following should be effective types of air-purifying respirators: Organic vapor cartridge
with a particulate pre-filter.
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Physical state Liquefied gas
Color brown
Odor musty
Odor Threshold 0.4 ppm Based on Literature for MDI. Odor is inadequate
warning of excessive exposure.
pH Not applicable
Melting point/range No test data available
Freezing point No test data available
Boiling point (760 mmHg) No test data available
Flash point closed cup Gas
Evaporation Rate (Butyl Acetate
= 1)
No test data available
Flammability (solid, gas) No data available
Lower explosion limit No test data available
Upper explosion limit No test data available
Vapor Pressure 1,551.3 kN/m2 at 54 C (129 F) Container is under pressure.
Relative Vapor Density (air = 1) No test data available
Relative Density (water = 1) 1.24 at 25 C (77 F) / 25 C Estimated.
Water solubility insoluble, reacts, evolution of CO2
Partition coefficient: n-
octanol/water
No data available
Auto-ignition temperature No test data available
Decomposition temperature No test data available
Kinematic Viscosity No test data available
Explosive properties Not explosive
Oxidizing properties No
Molecular weight No test data available
NOTE: The physical data presented above are typical values and should not be construed as a
specification.
10. STABILITY AND REACTIVITY
Reactivity: No data available
Chemical stability: Stable under recommended storage conditions. See Storage, Section 7.
Possibility of hazardous reactions: Can occur. Elevated temperatures can cause hazardous
polymerization. Polymerization can be catalyzed by: Strong bases. Water.
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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Conditions to avoid: Exposure to elevated temperatures can cause product to decompose. Elevated
temperatures can cause pressure buildup in closed containers due to the release of blowing agents.
Generation of gas during decomposition can cause pressure in closed systems. Pressure build-up
can be rapid. Avoid moisture. Material reacts slowly with water, releasing carbon dioxide which can
cause pressure buildup and rupture of closed containers. Elevated temperatures accelerate this
reaction.
Incompatible materials: Avoid contact with: Acids. Alcohols. Amines. Water. Ammonia. Bases.
Metal compounds. Moist air. Strong oxidizers. Diisocyanates react with many materials and the rate
of reaction increases with temperature as well as increased contact; these reactions can become
violent. Contact is increased by stirring or if the other material mixes with the diisocyanate.
Diisocyanates are not soluble in water and sink to the bottom, but react slowly at the interface. The
reaction forms carbon dioxide gas and a layer of solid polyurea. Reaction with water will generate
carbon dioxide and heat. Avoid contact with metals such as: Aluminum. Zinc. Brass. Tin. Copper.
Galvanized metals. Avoid contact with absorbent materials such as: Moist organic absorbents. Avoid
unintended contact with polyols. The reaction of polyols and isocyanates generate heat.
Hazardous decomposition products: Decomposition products depend upon temperature, air supply
and the presence of other materials. Gases are released during decomposition.
11. TOXICOLOGICAL INFORMATION
Toxicological information appears in this section when such data is available.
Acute toxicity
Acute oral toxicity
Low toxicity if swallowed. Small amounts swallowed incidentally as a result of normal
handling operations are not likely to cause injury; however, swallowing larger amounts may
cause injury.
As product: Single dose oral LD50 has not been determined.
LD50, Rat, > 2,000 mg/kg Estimated.
Acute dermal toxicity
Prolonged skin contact is unlikely to result in absorption of harmful amounts.
As product: The dermal LD50 has not been determined.
LD50, Rabbit, > 2,000 mg/kg Estimated.
Acute inhalation toxicity
In confined or poorly ventilated areas, vapor can easily accumulate and can cause
unconsciousness and death due to displacement of oxygen. Excessive exposure may cause
irritation to upper respiratory tract (nose and throat) and lungs. May cause pulmonary edema
(fluid in the lungs.) Effects may be delayed. Decreased lung function has been associated
with overexposure to isocyanates. Excessive exposure may increase sensitivity to
epinephrine and increase myocardial irritability (irregular heartbeats). May cause central
nervous system effects. Symptoms of excessive exposure may be anesthetic or narcotic
effects; dizziness and drowsiness may be observed.
As product: The LC50 has not been determined.
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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Skin corrosion/irritation
Prolonged contact may cause skin irritation with local redness.
May stain skin.
Serious eye damage/eye irritation
May cause moderate eye irritation.
May cause slight temporary corneal injury.
Sensitization
Skin contact may cause an allergic skin reaction.
Animal studies have shown that skin contact with isocyanates may play a role in respiratory
sensitization.
May cause allergic respiratory reaction.
MDI concentrations below the exposure guidelines may cause allergic respiratory reactions in
individuals already sensitized.
Asthma-like symptoms may include coughing, difficult breathing and a feeling of tightness in the chest.
Occasionally, breathing difficulties may be life threatening.
Specific Target Organ Systemic Toxicity (Single Exposure)
Contains component(s) which are classified as specific target organ toxicant, single exposure,
category 3.
Specific Target Organ Systemic Toxicity (Repeated Exposure)
Tissue injury in the upper respiratory tract and lungs has been observed in laboratory animals after
repeated excessive exposures to MDI/polymeric MDI aerosols.
Carcinogenicity
Lung tumors have been observed in laboratory animals exposed to respirable aerosol droplets of
MDI/Polymeric MDI (6 mg/m3) for their lifetime. Tumors occurred concurrently with respiratory
irritation and lung injury. Current exposure guidelines are expected to protect against these effects
reported for MDI.
Teratogenicity
In laboratory animals, MDI/polymeric MDI did not cause birth defects; other fetal effects occurred only
at high doses which were toxic to the mother. Contains component(s) which did not cause birth
defects in animals; other fetal effects occurred only at doses toxic to the mother.
Reproductive toxicity
No relevant data found.
Mutagenicity
Genetic toxicity data on MDI are inconclusive. MDI was weakly positive in some in vitro studies; other
in vitro studies were negative. Animal mutagenicity studies were predominantly negative.
Aspiration Hazard
Based on physical properties, not likely to be an aspiration hazard.
COMPONENTS INFLUENCI NG TOXICOLOGY:
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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Diphenylmethane Diisocyanate, isomers and homologues
Acute inhalation toxicity
LC50, Rat, 4 Hour, dust/mist, 0.49 mg/l
For similar material(s): 4,4′-Methylenediphenyl diisocyanate (CAS 101-68-8). LC50, Rat, 1
Hour, Aerosol, 2.24 mg/l
For similar material(s): 2,4′-Diphenylmethane diisocyanate (CAS 5873-54-1). LC50, Rat, 4
Hour, Aerosol, 0.387 mg/l
4,4′-Methylenediphenyl diisocyanate
Acute inhalation toxicity
LC50, Rat, 1 Hour, dust/mist, 2.24 mg/l
1,1,1,2-Tetrafluoroethane
Acute inhalation toxicity
LC50, Rat, 4 Hour, vapour, > 1,500 mg/l
12. ECOLOGICAL INFORMATION
Ecotoxicological information appears in this section when such data is available.
Toxicity
Diphenylmethane Diisocyanate, isomers and homologues
Acute toxicity to fish
The measured ecotoxicity is that of the hydrolyzed product, generally under conditions
maximizing production of soluble species.
Material is practically non-toxic to aquatic organisms on an acute basis
(LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested).
Based on information for a similar material:
LC50, Danio rerio (zebra fish), static test, 96 Hour, > 1,000 mg/l, OECD Test Guideline 203 or
Equivalent
Acute toxicity to aquatic invertebrates
Based on information for a similar material:
EC50, Daphnia magna (Water flea), static test, 24 Hour, > 1,000 mg/l, OECD Test Guideline
202 or Equivalent
Acute toxicity to algae/aquatic plants
Based on information for a similar material:
NOEC, Desmodesmus subspicatus (green algae), static test, 72 Hour, Growth rate inhibition,
1,640 mg/l, OECD Test Guideline 201 or Equivalent
Toxicity to bacteria
Based on information for a similar material:
EC50, activated sludge, static test, 3 Hour, Respiration rates., > 100 mg/l
Toxicity to soil-dwelling organisms
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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EC50, Eisenia fetida (earthworms), Based on information for a similar material:, 14 d, > 1,000
mg/kg
Toxicity to terrestrial plants
EC50, Avena sativa (oats), Growth inhibition, 1,000 mg/l
EC50, Lactuca sativa (lettuce), Growth inhibition, 1,000 mg/l
4,4′-Methylenediphenyl diisocyanate
Acute toxicity to fish
The measured ecotoxicity is that of the hydrolyzed product, generally under conditions
maximizing production of soluble species.
Material is practically non-toxic to aquatic organisms on an acute basis
(LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested).
Based on information for a similar material:
LC50, Danio rerio (zebra fish), static test, 96 Hour, > 1,000 mg/l, OECD Test Guideline 203 or
Equivalent
Acute toxicity to aquatic invertebrates
Based on information for a similar material:
EC50, Daphnia magna (Water flea), static test, 24 Hour, > 1,000 mg/l, OECD Test Guideline
202 or Equivalent
Acute toxicity to algae/aquatic plants
Based on information for a similar material:
NOEC, Desmodesmus subspicatus (green algae), static test, 72 Hour, Growth rate inhibition,
1,640 mg/l, OECD Test Guideline 201 or Equivalent
Toxicity to bacteria
Based on information for a similar material:
EC50, activated sludge, static test, 3 Hour, Respiration rates., > 100 mg/l
Toxicity to soil-dwelling organisms
EC50, Eisenia fetida (earthworms), Based on information for a similar material:, 14 d, > 1,000
mg/kg
Toxicity to terrestrial plants
EC50, Avena sativa (oats), Growth inhibition, 1,000 mg/l
EC50, Lactuca sativa (lettuce), Growth inhibition, 1,000 mg/l
1,1,1,2-Tetrafluoroethane
Acute toxicity to fish
Material is practically non-toxic to aquatic organisms on an acute basis
(LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested).
LC50, Oncorhynchus mykiss (rainbow trout), semi-static test, 96 Hour, 450 mg/l
Acute toxicity to aquatic invertebrates
EC50, Daphnia magna (Water flea), 48 Hour, 980 mg/l
Toxicity to bacteria
EC50, Pseudomonas putida, static test, 6 Hour, Growth inhibition, > 730 mg/l
Persistence and degradability
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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Diphenylmethane Diisocyanate, isomers and homologues
Biodegradability: In the aquatic and terrestrial environment, material reacts with water
forming predominantly insoluble polyureas which appear to be stable. In the atmospheric
environment, material is expected to have a short tropospheric half-life, based on calculations
and by analogy with related diisocyanates.
10-day Window: Not applicable
Biodegradation: 0 %
Exposure time: 28 d
Method: OECD Test Guideline 302C or Equivalent
4,4′-Methylenediphenyl diisocyanate
Biodegradability: In the aquatic and terrestrial environment, material reacts with water
forming predominantly insoluble polyureas which appear to be stable. In the atmospheric
environment, material is expected to have a short tropospheric half-life, based on calculations
and by analogy with related diisocyanates.
10-day Window: Not applicable
Biodegradation: 0 %
Exposure time: 28 d
Method: OECD Test Guideline 302C or Equivalent
1,1,1,2-Tetrafluoroethane
Biodegradability: Material is expected to biodegrade very slowly (in the environment). Fails
to pass OECD/EEC tests for ready biodegradability.
10-day Window: Fail
Biodegradation: 4 %
Exposure time: 28 d
Method: OECD Test Guideline 301D or Equivalent
Theoretical Oxygen Demand: 0.47 mg/mg
Photodegradation
Test Type: Half-life (indirect photolysis)
Sensitization: OH radicals
Atmospheric half-life: 1,700 d
Method: Estimated.
Bioaccumulative potential
Diphenylmethane Diisocyanate, isomers and homologues
Bioaccumulation: Bioconcentration potential is low (BCF < 100 or Log Pow < 3). Reacts with
water. In the aquatic and terrestrial environment, movement is expected to be limited by its
reaction with water forming predominantly insoluble polyureas.
Bioconcentration factor (BCF): 92 Cyprinus carpio (Carp) 28 d
4,4'-Methylenediphenyl diisocyanate
Bioaccumulation: Bioconcentration potential is low (BCF < 100 or Log Pow < 3). Reacts with
water. In the aquatic and terrestrial environment, movement is expected to be limited by its
reaction with water forming predominantly insoluble polyureas.
Bioconcentration factor (BCF): 92 Cyprinus carpio (Carp) 28 d
1,1,1,2-Tetrafluoroethane
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
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Bioaccumulation: Bioconcentration potential is low (BCF < 100 or Log Pow < 3).
Partition coefficient: n-octanol/water(log Pow): 1.68 Estimated.
Mobility in soil
Diphenylmethane Diisocyanate, isomers and homologues
In the aquatic and terrestrial environment, movement is expected to be limited by its reaction
with water forming predominantly insoluble polyureas.
4,4'-Methylenediphenyl diisocyanate
In the aquatic and terrestrial environment, movement is expected to be limited by its reaction
with water forming predominantly insoluble polyureas.
1,1,1,2-Tetrafluoroethane
Potential for mobility in soil is high (Koc between 50 and 150).
Partition coefficient (Koc): 97 Estimated.
13. DISPOSAL CONSIDERATIONS
Disposal methods: DO NOT DUMP INTO ANY SEWERS, ON THE GROUND, OR INTO ANY BODY
OF WATER. All disposal practices must be in compliance with all Federal, State/Provincial and local
laws and regulations. Regulations may vary in different locations. Waste characterizations and
compliance with applicable laws are the responsibility solely of the waste generator. AS YOUR
SUPPLIER, WE HAVE NO CONTROL OVER THE MANAGEMENT PRACTICES OR
MANUFACTURING PROCESSES OF PARTIES HANDLING OR US ING THIS MATERIAL. THE
INFORMATION PRESENTED HERE PERTAINS ONLY TO THE PRODUCT AS SHIPPED IN ITS
INTENDED CONDITION AS DESCRIBED IN MSDS SECTION: Composition Information. FOR
UNUSED & UNCONTAMINATED PRODUCT, the preferred options include sending to a licensed,
permitted: Recycler. Reclaimer. Incinerator or other thermal destruction device. For additional
information, refer to: Handling & Storage Information, MSDS Section 7 Stability & Reactivity
Information, MSDS Section10 Regulatory Information, MSDS Section 15
14. TRANSPORT INFORMATION
DOT
Proper shipping name Chemical under pressure, n.o.s.(1,1,1,2-Tetrafluoroethane)
UN number UN 3500
Class 2.2
Packing group
Reportable Quantity MDI
Classification for SEA transport (IMO-IMDG):
Proper shipping name CHEMICAL UNDER PRESSURE, N.O.S. (1,1,1,2-
Tetrafluoroethane)
UN number UN 3500
Class 2.2
Packing group
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
Page 14 of 16
Marine pollutant No
Transport in bulk
according to Annex I or II
of MARPOL 73/78 and the
IBC or IGC Code
Consult IMO regulations before transporting ocean bulk
Classification for AIR transport (IATA/ICAO):
Proper shipping name Chemical under pressure, n.o.s.(1,1,1,2-Tetrafluoroethane)
UN number UN 3500
Class 2.2
Packing group
This information is not intended to convey all specific regulatory or operational
requirements/information relating to this product. Transportation classifications may vary by container
volume and may be influenced by regional or country variations in regulations. Additional
transportation system information can be obtained through an authorized sales or customer service
representative. It is the responsibility of the transporting organization to follow all applicable laws,
regulations and rules relating to the transportation of the material.
15. REGULATORY INFORMATION
Superfund Amendments and Reauthorization Act of 1986 Title III (Emergency Planning and
Community Right-to-Know Act of 1986) Sections 311 and 312
Gases under pressure
Acute toxicity (any route of exposure)
Skin corrosion or irritation
Serious eye damage or eye irritation
Respiratory or skin sensitisation
Specific target organ toxicity (single or repeated exposure)
Superfund Amendments and Reauthorization Act of 1986 Title III (Emergency Planning and
Community Right-to-Know Act of 1986) Section 313
This product contains the following substances which are subject to the reporting requirements of
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 and which are
listed in 40 CFR 372.
Components CASRN
Diphenylmethane Diisocyanate, isomers and homologues 9016-87-9
4,4'-Methylenediphenyl diisocyanate 101-68-8
Pennsylvania Worker and Community Right-To-Know Act:
To the best of our knowledge, this product does not contain chemicals at levels which require reporting
under this statute.
California Proposition 65 (Safe Drinking Water and Toxic Enforcement Act of 1986)
This product contains no listed substances known to the State of California to cause cancer, birth
defects or other reproductive harm, at levels which would require a warning under the statute.
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
Page 15 of 16
United States TSCA Inventory (TSCA)
All components of this product are in compliance with the inventory listing requirements of the U.S.
Toxic Substances Control Act (TSCA) Chemical Substance Inventory.
16. OTHER INFORMATION
Revision
Identification Number: 158170 / A749 / Issue Date: 10/17/2018 / Version: 2.0
Most recent revision(s) are noted by the bold, double bars in left-hand margin throughout this
document.
Legend
ACGIH USA. ACGIH Threshold Limit Values (TLV)
C Ceiling
Dow IHG Dow Industrial Hygiene Guideline
OSHA Z-1 USA. Occupational Exposure Limits (OSHA) - Table Z-1 Limits for Air
Contaminants
STEL Short term exposure limit
TWA Time weighted average
US WEEL USA. Workplace Environmental Exposure Levels (WEEL)
Full text of other abbreviations
AICS - Australian Inventory of Chemical Substances; ASTM - American Society for the Testing of
Materials; bw - Body weight; CERCLA - Comprehensive Environmental Response, Compensation,
and Liability Act; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard of the
German Institute for Standardisation; DOT - Department of Transportation; DSL - Domestic
Substances List (Canada); ECx - Concentration associated with x% response; EHS - Extremely
Hazardous Substance; ELx - Loading rate associated with x% response; EmS - Emergency Schedule;
ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with x%
growth rate response; ERG - Emergency Response Guide; GHS - Globally Harmonized System; GLP
- Good Laboratory Practice; HMIS - Hazardous Materials Identification System; IARC - International
Agency for Research on Cancer; IATA - International Air Transport Association; IBC - International
Code for the Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half
maximal inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of
Existing Chemical Substances in China; IMDG - International Maritime Dangerous Goods; IMO -
International Maritime Organization; ISHL - Industrial Safety and Health Law (Japan); ISO -
International Organisation for Standardization; KECI - Korea Existing Chemicals Inventory; LC50 -
Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test population
(Median Lethal Dose); MARPOL - International Convention for the Prevention of Pollution from Ships;
MSHA - Mine Safety and Health Administration; n.o.s. - Not Otherwise Specified; NFPA - National Fire
Protection Association; NO(A)EC - No Observed (Adverse) Effect Concentration; NO(A)EL - No
Observed (Adverse) Effect Level; NOELR - No Observable Effect Loading Rate; NTP - National
Toxicology Program; NZIoC - New Zealand Inventory of Chemicals; OECD - Organization for
Economic Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution
Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of
Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure Activity Relationship; RCRA -
Resource Conservation and Recovery Act; REACH - Regulation (EC) No 1907/2006 of the European
Product name: FROTH-PAK ISO INT AF HFC Issue Date: 10/17/2018
Page 16 of 16
Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of
Chemicals; RQ - Reportable Quantity; SADT - Self-Accelerating Decomposition Temperature; SARA -
Superfund Amendments and Reauthorization Act; SDS - Safety Data Sheet; TCSI - Taiwan Chemical
Substance Inventory; TSCA - Toxic Substances Control Act (United States); UN - United Nations;
UNRTDG - United Nations Recommendations on the Transport of Dangerous Goods; vPvB - Very
Persistent and Very Bioaccumulative
Information Source and References
This SDS is prepared by Product Regulatory Services and Hazard Communications Groups from
information supplied by internal references within our company.
DDP SPECIALTY ELECTRONIC MATERIALS US, INC. urges each customer or recipient of this
(M)SDS to study it carefully and consult appropriate expertise, as necessary or appropriate, to become
aware of and understand the data contained in this (M)SDS and any hazards associated with the
product. The information herein is provided in good faith and believed to be accurate as of the
effective date shown above. However, no warranty, express or implied, is given. Regulatory
requirements are subject to change and may differ between various locations. It is the buyer's/user's
responsibility to ensure that his activities comply with all federal, state, provincial or local laws. The
information presented here pertains only to the product as shipped. Since conditions for use of the
product are not under the control of the manufacturer, it is the buyer's/user's duty to determine the
conditions necessary for the safe use of this product. Due to the proliferation of sources for
information such as manufacturer-specific (M)SDSs, we are not and cannot be responsible for
(M)SDSs obtained from any source other than ourselves. If you have obtained an (M)SDS from
another source or if you are not sure that the (M)SDS you have is current, please contact us for the
most current version.
US