Page: 1
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
1 / 20
29 CFR 1910.1200 (OSHA HazCom 2012)
SECTION 1. PRODUCT AND COMPANY IDENTIFICATION
Product identifier
Trade name : BLO
butyrolactone
Trademark, Ashland or its subsidiaries, registered in
various countries
Substance name : -butyrolactone
Substance No.
EC-No. : 202-509-5
CAS-No. : 96-48-0
Relevant identified uses of the substance or mixture and uses advised against
Recommended use
: Solvent.
Intermediate.
Laboratory chemicals
Viscosity adjustors
Restrictions on use
: Cosmetics
Soluble coatings on children’s toys
Details of the supplier of the safety data
sheet
Ashland
P.O. Box 2219
Columbus, OH 43216
United States of America (USA)
+1-614-790-3333
EHSProductSafety@ashland.com
Emergency telephone number
1-800-ASHLAND (1-800-274-5263)
Regulatory Information Number
1-800-325-3751
Product Information
+1-614-790-3333
SECTION 2. HAZARDS IDENTIFICATION
GHS Classification
Acute toxicity (Oral)
: Category 4
Serious eye damage : Category 1
Page: 2
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
2 / 20
Specific target organ
systemic toxicity – single
exposure
: Category 3 (Central nervous system)
GHS label elements
Hazard pictograms
:
Signal Word
: Danger
Hazard Statements
: Harmful if swallowed.
Causes serious eye damage.
May cause drowsiness or dizziness.
Precautionary Statements
: Prevention:
Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
Wash skin thoroughly after handling.
Do not eat, drink or smoke when using this product.
Use only outdoors or in a well-ventilated area.
Wear eye protection/ face protection.
Response:
IF SWALLOWED: Call a POISON CENTER/doctor if you feel
unwell. Rinse mouth.
IF INHALED: Remove person to fresh air and keep comfortable
for breathing. Call a POISON CENTER/doctor if you feel unwell.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing. Immediately call a POISON CENTER/doctor.
Storage:
Store in a well-ventilated place. Keep container tightly closed.
Store locked up.
Disposal:
Dispose of contents/ container to an approved waste disposal
plant.
Other hazards
None known.
SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance / Mixture
: Substance
Page: 3
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
3 / 20
Hazardous components
Chemical name CAS-No. Classification Concentration (%)
BUTYROLACTONE 96-48-0 Acute Tox. 4; H302
Eye Dam. 1; H318
STOT SE 3; H336
99.80
SECTION 4. FIRST AID MEASURES
General advice
: Move out of dangerous area.
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Do not leave the victim unattended.
If inhaled
: Move to fresh air.
Keep patient warm and at rest.
If unconscious, place in recovery position and seek medical
advice.
Consult a physician after significant exposure.
In case of skin contact
: First aid is not normally required. However, it is
recommended that exposed areas be cleaned by washing
with soap and water.
In case of eye contact
: In the case of contact with eyes, rinse immediately with plenty
of water and seek medical advice.
Continue rinsing eyes during transport to hospital.
Remove contact lenses.
Protect unharmed eye.
If swallowed
: Obtain medical attention.
Do NOT induce vomiting.
Rinse mouth with water.
Do not give milk or alcoholic beverages.
Never give anything by mouth to an unconscious person.
If symptoms persist, call a physician.
Most important symptoms
and effects, both acute and
delayed
:
Signs and symptoms of exposure to this material through
breathing, swallowing, and/or passage of the material through
the skin may include:
effects on blood pressure
Page: 4
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
4 / 20
Harmful if swallowed.
Causes serious eye damage.
May cause drowsiness or dizziness.
Notes to physician
: No hazards which require special first aid measures.
SECTION 5. FIREFIGHTING MEASURES
Suitable extinguishing media
: Use extinguishing measures that are appropriate to local
circumstances and the surrounding environment.
Water spray
Foam
Carbon dioxide (CO2)
Dry chemical
Unsuitable extinguishing
media
: High volume water jet
Specific hazards during
firefighting
: If product is heated above its flash point it will produce vapors
sufficient to support combustion. Vapors are heavier than air
and may travel along the ground and be ignited by heat, pilot
lights, other flames and ignition sources at locations near the
point of release.
Do not allow run-off from fire fighting to enter drains or water
courses.
Hazardous combustion
products
: carbon dioxide and carbon monoxide
nitrogen oxides (NOx)
Hydrocarbons
toxic fumes
Specific extinguishing
methods
:
Product is compatible with standard fire-fighting agents.
Further information : Fire residues and contaminated fire extinguishing water must
be disposed of in accordance with local regulations.
Special protective equipment
for firefighters
: In the event of fire, wear self-contained breathing apparatus.
SECTION 6. ACCIDENTAL RELEASE MEASURES
Page: 5
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
5 / 20
Personal precautions,
protective equipment and
emergency procedures
: Use personal protective equipment.
Ensure adequate ventilation.
Persons not wearing protective equipment should be excluded
from area of spill until clean-up has been completed.
Environmental precautions
: Prevent product from entering drains.
Prevent further leakage or spillage if safe to do so.
If the product contaminates rivers and lakes or drains inform
respective authorities.
Methods and materials for
containment and cleaning up
: Soak up with inert absorbent material (e.g. sand, silica gel,
acid binder, universal binder, sawdust).
Keep in suitable, closed containers for disposal.
Other information
: Comply with all applicable federal, state, and local regulations.
SECTION 7. HANDLING AND STORAGE
Advice on safe handling
: Avoid formation of aerosol.
Provide sufficient air exchange and/or exhaust in work rooms.
Do not breathe vapours/dust.
Do not smoke.
Container hazardous when empty.
Avoid exposure – obtain special instructions before use.
Avoid contact with skin and eyes.
Smoking, eating and drinking should be prohibited in the
application area.
For personal protection see section 8.
Dispose of rinse water in accordance with local and national
regulations.
Conditions for safe storage
: Keep container tightly closed in a dry and well-ventilated
place.
Containers which are opened must be carefully resealed and
kept upright to prevent leakage.
Observe label precautions.
SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Hazardous components without workplace control parameters
Page: 6
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
6 / 20
Components CAS-No.
BUTYROLACTONE 96-48-0
Engineering measures : Provide sufficient mechanical (general and/or local exhaust)
ventilation to maintain exposure below exposure guidelines (if
applicable) or below levels that cause known, suspected or
apparent adverse effects.
Personal protective equipment
Respiratory protection : In the case of vapour formation use a respirator with an
approved filter within the capabilities of the respirator/filter
combination.
Where concentrations are above recommended limits or are
unknown, or a cartridge type respirator is not adequate, wear
a positive-pressure supplied-air respirator.
Hand protection
Material : butyl-rubber
Break through time : 480 min
Glove thickness : > 0.5 mm
Remarks : The exact break through time can be obtained from the
protective glove producer and this has to be observed. Gloves
should be discarded and replaced if there is any indication of
degradation or chemical breakthrough.
Eye protection : Wear chemical splash goggles and face shield when there is
potential for exposure of the eyes or face to liquid, vapor or
mist.
Maintain eye wash station in immediate work area.
Skin and body protection : Wear as appropriate:
Impervious clothing
Safety shoes
Choose body protection according to the amount and
concentration of the dangerous substance at the work place.
Wear resistant gloves (consult your safety equipment
supplier).
Hygiene measures : Wash hands before breaks and at the end of workday.
When using do not eat or drink.
When using do not smoke.
SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state : liquid
Page: 7
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
7 / 20
Colour
: clear
Odour
: mild
Odour Threshold
: No data available
pH
: 4.5
Concentration: 10 %
Melting point/freezing point
: -47 – -44 F / -44 – -42 C
Boiling point/boiling range
: 400.3 F / 204.6 C
Flash point
: 106 C
Evaporation rate
: No data available
Flammability (solid, gas)
: No data available
Upper explosion limit
: No data available
Lower explosion limit
: No data available
Vapour pressure
: 0.344 hPa (20 C)
Relative vapour density
: No data available
Relative density
: No data available
Density
: 1.124 g/cm3 (25 C)
Solubility(ies)
Water solubility
: completely miscible
Solubility in other solvents
: No data available
Partition coefficient: n-
octanol/water
: log Pow: -0.566
Thermal decomposition
: No data available
Viscosity
Viscosity, dynamic : 2 mPa.s (20 C)
Page: 8
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
8 / 20
Viscosity, kinematic
: No data available
Oxidizing properties
: No data available
SECTION 10. STABILITY AND REACTIVITY
Reactivity
: No decomposition if stored and applied as directed.
Chemical stability
: Stable under recommended storage conditions.
Possibility of hazardous
reactions
: Product will not undergo hazardous polymerization.
Incompatible materials
: Strong oxidizing agents
Hazardous decomposition
products
carbon dioxide and carbon monoxide
Hydrocarbons
Nitrogen oxides (NOx)
SECTION 11. TOXICOLOGICAL INFORMATION
Information on likely routes of
exposure
: Inhalation
Skin contact
Eye Contact
Ingestion
Acute toxicity
Harmful if swallowed.
Product:
Acute oral toxicity
: LD50 (Rat): 1,582 mg/kg
Acute inhalation toxicity
: LC50 (Rat): > 5.1 mg/l
Exposure time: 4 h
Test atmosphere: dust/mist
Acute dermal toxicity
: LD50 (Guinea pig): > 5 g/kg
Components:
BUTYROLACTONE :
Acute oral toxicity : LD50 (Rat): 1,582 mg/kg
Page: 9
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
9 / 20
Acute inhalation toxicity
: LC50 (Rat): > 5.1 mg/l
Exposure time: 4 h
Test atmosphere: dust/mist
Acute dermal toxicity
: LD50 (Guinea pig): > 5 g/kg
Skin corrosion/irritation
Not classified based on available information.
Product:
Result: No skin irritation
Components:
BUTYROLACTONE :
Result: No skin irritation
Serious eye damage/eye irritation
Causes serious eye damage.
Product:
Remarks: May cause irreversible eye damage.
Result: Corrosive
Components:
BUTYROLACTONE :
Result: Corrosive
Respiratory or skin sensitisation
Skin sensitisation: Not classified based on available information.
Respiratory sensitisation: Not classified based on available information.
Product:
Test Type: Local lymph node assay
Species: Mouse
Assessment: Does not cause skin sensitisation.
Result: negative
Components:
BUTYROLACTONE :
Test Type: Local lymph node assay
Species: Mouse
Assessment: Does not cause skin sensitisation.
Result: negative
Germ cell mutagenicity
Not classified based on available information.
Page: 10
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
10 / 20
Product:
Genotoxicity in vitro
: Test Type: Ames test
Result: negative
: Test Type: Chromosome aberration test in vitro
Result: negative
Genotoxicity in vivo
: Test Type: In vivo micronucleus test
Test species: Mouse
Result: negative
Components:
BUTYROLACTONE :
Genotoxicity in vitro
: Test Type: Ames test
Result: negative
: Test Type: Chromosome aberration test in vitro
Result: negative
Genotoxicity in vivo
: Test Type: In vivo micronucleus test
Test species: Mouse
Result: negative
Carcinogenicity
Not classified based on available information.
Product:
Species: Rat, (male)
Application Route: Oral
NOAEL: 225 mg/kg bw/day
Result: negative
Target Organs: No specific target organs noted
GLP: yes
Remarks: No significant adverse effects were reported
Species: Rat, (female)
Application Route: Oral
NOAEL: 225 mg/kg bw/day
Result: negative
Target Organs: No specific target organs noted
GLP: yes
Remarks: Significant toxicity observed in testing
Species: Mouse, (male and female)
Application Route: Oral
NOAEL: 262 mg/kg bw/day
Result: negative
Target Organs: No specific target organs noted
Page: 11
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
11 / 20
GLP: yes
Remarks: Significant toxicity observed in testing
Components:
BUTYROLACTONE :
Species: Rat, (male)
Application Route: Oral
NOAEL: 225 mg/kg bw/day
Result: negative
Target Organs: No specific target organs noted
GLP: yes
Remarks: No significant adverse effects were reported
Species: Rat, (female)
Application Route: Oral
NOAEL: 225 mg/kg bw/day
Result: negative
Target Organs: No specific target organs noted
GLP: yes
Remarks: Significant toxicity observed in testing
Species: Mouse, (male and female)
Application Route: Oral
NOAEL: 262 mg/kg bw/day
Result: negative
Target Organs: No specific target organs noted
GLP: yes
Remarks: Significant toxicity observed in testing
Reproductive toxicity
Not classified based on available information.
Product:
Effects on foetal
development
: Species: Rat, male and female
Strain: Sprague-Dawley
Application Route: Oral
Dose: 0,10,50,125,500 mg/kg bw/day
Duration of Single Treatment: 21 d
General Toxicity Maternal: 500 mg/kg bw/day
Teratogenicity: 500 mg/kg bw/day
Result: No teratogenic effects
GLP: no
Remarks: No significant adverse effects were reported
Components:
BUTYROLACTONE :
Effects on foetal
development
: Species: Rat, male and female
Strain: Sprague-Dawley
Page: 12
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
12 / 20
Application Route: Oral
Dose: 0,10,50,125,500 mg/kg bw/day
Duration of Single Treatment: 21 d
General Toxicity Maternal: 500 mg/kg bw/day
Teratogenicity: 500 mg/kg bw/day
Result: No teratogenic effects
GLP: no
Remarks: No significant adverse effects were reported
STOT – single exposure
May cause drowsiness or dizziness.
Components:
BUTYROLACTONE :
Exposure routes: Inhalation
Assessment: The substance or mixture is classified as specific target organ toxicant, single
exposure, category 3 with narcotic effects.
STOT – repeated exposure
Not classified based on available information.
Repeated dose toxicity
Product:
Species: Rat, male
NOAEL: 225 mg/kg
Application Route: Oral
Exposure time: CUST-N11.00322330
Method: Gavage
GLP: yes
Target Organs: No specific target organs noted
Species: Rat, female
NOAEL: 450 mg/kg
Application Route: Oral
Exposure time: CUST-N11.00322330
Method: Gavage
GLP: yes
Target Organs: No specific target organs noted
Species: Mouse, male and female
NOAEL: 525 mg/kg
Application Route: Oral
Exposure time: CUST-N11.00322330
Method: Gavage
GLP: yes
Target Organs: No specific target organs noted
Components:
BUTYROLACTONE :
Page: 13
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
13 / 20
Species: Rat, male
NOAEL: 225 mg/kg
Application Route: Oral
Exposure time: CUST-N11.00322330
Method: Gavage
GLP: yes
Target Organs: No specific target organs noted
Species: Rat, female
NOAEL: 450 mg/kg
Application Route: Oral
Exposure time: CUST-N11.00322330
Method: Gavage
GLP: yes
Target Organs: No specific target organs noted
Species: Mouse, male and female
NOAEL: 525 mg/kg
Application Route: Oral
Exposure time: CUST-N11.00322330
Method: Gavage
GLP: yes
Target Organs: No specific target organs noted
Aspiration toxicity
Not classified based on available information.
Further information
Product:
Remarks: Symptoms of overexposure may be headache, dizziness, tiredness, nausea and
vomiting., Concentrations substantially above the TLV value may cause narcotic effects.,
Solvents may degrease the skin.
Carcinogenicity:
IARC
No component of this product present at levels greater than or
equal to 0.1% is identified as probable, possible or confirmed
human carcinogen by IARC.
OSHA
No component of this product present at levels greater than or
equal to 0.1% is on OSHA s list of regulated carcinogens.
NTP
No component of this product present at levels greater than or
equal to 0.1% is identified as a known or anticipated carcinogen
by NTP.
Page: 14
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
14 / 20
SECTION 12. ECOLOGICAL INFORMATION
Ecotoxicity
Product:
Toxicity to fish
: LC50 (Lepomis macrochirus (Bluegill sunfish)): 56 mg/l
Exposure time: 96 h
Test Type: static test
Toxicity to daphnia and other
aquatic invertebrates
: EC50 (Daphnia magna (Water flea)): > 500 mg/l
Exposure time: 48 h
Toxicity to algae
: ErC50 (Desmodesmus subspicatus (green algae)): > 1,000
mg/l
EC10 (Desmodesmus subspicatus (green algae)): 84.4 mg/l
Toxicity to bacteria
: IC50 (Ciliate (Tetrahymena pyriformis)): 4,518 mg/l
Ecotoxicology Assessment
Short-term (acute) aquatic
hazard
: Acute aquatic toxicity Category 3; Harmful to aquatic life.
Long-term (chronic) aquatic
hazard
: Not classified based on available information.
Components:
BUTYROLACTONE :
Toxicity to fish
: LC50 (Lepomis macrochirus (Bluegill sunfish)): 56 mg/l
Exposure time: 96 h
Test Type: static test
Toxicity to daphnia and other
aquatic invertebrates
: EC50 (Daphnia magna (Water flea)): > 500 mg/l
Exposure time: 48 h
Toxicity to algae
: ErC50 (Desmodesmus subspicatus (green algae)): > 1,000
mg/l
EC10 (Desmodesmus subspicatus (green algae)): 84.4 mg/l
Toxicity to bacteria
: IC50 (Ciliate (Tetrahymena pyriformis)): 4,518 mg/l
Persistence and degradability
Product:
Biodegradability
: Result: Readily biodegradable.
Biodegradation: 95 %
Exposure time: 14 d
Page: 15
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
15 / 20
Components:
BUTYROLACTONE :
Biodegradability
: Result: Readily biodegradable.
Biodegradation: 95 %
Exposure time: 14 d
No data available
Bioaccumulative potential
Components:
BUTYROLACTONE :
Partition coefficient: n-
octanol/water
: log Pow: -0.566 (25 C)
No data available
Mobility in soil
Components:
No data available
Other adverse effects
Product:
Additional ecological
information
: An environmental hazard cannot be excluded in the event of
unprofessional handling or disposal., Harmful to aquatic life.
Components:
BUTYROLACTONE :
Results of PBT and vPvB
assessment
: This substance is not considered to be persistent,
bioaccumulating and toxic (PBT). This substance is not
considered to be very persistent and very bioaccumulating
(vPvB).
SECTION 13. DISPOSAL CONSIDERATIONS
Disposal methods
General advice : The product should not be allowed to enter drains, water
courses or the soil.
Do not contaminate ponds, waterways or ditches with
chemical or used container.
Send to a licensed waste management company.
Dispose of in accordance with all applicable local, state and
federal regulations.
Contaminated packaging : Empty remaining contents.
Dispose of as unused product.
Empty containers should be taken to an approved waste
Page: 16
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
16 / 20
handling site for recycling or disposal.
Do not re-use empty containers.
SECTION 14. TRANSPORT INFORMATION
International transport regulations
REGULATION
ID NUMBER PROPER SHIPPING NAME *HAZARD
CLASS
SUBSIDIARY
HAZARDS
PACKING
GROUP
MARINE
POLLUTANT /
LTD. QTY.
MX_DG
Not dangerous goods
INTERNATIONAL AIR TRANSPORT ASSOCIATION – PASSENGER
Not dangerous goods
INTERNATIONAL AIR TRANSPORT ASSOCIATION – CARGO
Not dangerous goods
INTERNATIONAL MARITIME DANGEROUS GOODS
Not dangerous goods
TDG_INWT_C
Not dangerous goods
TDG_RAIL_C
Not dangerous goods
TDG_ROAD_C
Not dangerous goods
U.S. DOT – INLAND WATERWAYS
Not dangerous goods
CFR_RAIL_C
Page: 17
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
17 / 20
Not dangerous goods
U.S. DOT – ROAD
Not dangerous goods
*ORM = ORM-D, CBL = COMBUSTIBLE LIQUID
Marine pollutant no
Dangerous goods descriptions (if indicated above) may not reflect quantity, end-use or region-specific
exceptions that can be applied. Consult shipping documents for descriptions that are specific to the
shipment.
SECTION 15. REGULATORY INFORMATION
EPCRA – Emergency Planning and Community Right-to-Know Act
CERCLA Reportable Quantity
This material does not contain any components with a CERCLA RQ.
SARA 304 Extremely Hazardous Substances Reportable Quantity
This material does not contain any components with a section 304 EHS RQ.
SARA 311/312 Hazards
: Acute toxicity (any route of exposure)
Serious eye damage or eye irritation
Specific target organ toxicity (single or repeated exposure)
SARA 302
: This material does not contain any components with a section
302 EHS TPQ.
SARA 313 This material does not contain any chemical components with
known CAS numbers that exceed the threshold (De Minimis)
reporting levels established by SARA Title III, Section 313.
Pennsylvania Right To Know
BUTYROLACTONE
96-48-0
New Jersey Right To Know
BUTYROLACTONE
96-48-0
California Prop. 65
This product does not contain any chemicals known to State of California to cause cancer, birth
defects, or any other reproductive harm.
The components of this product are reported in the following inventories:
Page: 18
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
826673
Version: 1.4
18 / 20
DSL
: All components of this product are on the Canadian DSL
AICS
: On the inventory, or in compliance with the inventory
ENCS
: On the inventory, or in compliance with the inventory
KECI
: On the inventory, or in compliance with the inventory
PICCS
: On the inventory, or in compliance with the inventory
IECSC
: On the inventory, or in compliance with the inventory
TSCA
: For Cosmetic Use Only
Inventories
AICS (Australia), DSL (Canada), IECSC (China), REACH (European Union), ENCS (Japan), ISHL
(Japan), KECI (Korea), NZIoC (New Zealand), PICCS (Philippines), TCSI (Taiwan), TSCA (USA)
SECTION 16. OTHER INFORMATION
Further information
Revision Date: 08/31/2018
NFPA: HMIS III:
NFPA Flammable and Combustible Liquids Classification
Combustible Liquid Class IIIB
Full text of H-Statements
H302 Harmful if swallowed.
Flammability
Health
Instability
3
1
0
FLAMMABILITY
PHYSICAL HAZARD
HEALTH
1
0
3/
Special hazard.
0 = not significant, 1 =Slight,
2 = Moderate, 3 = High
4 = Extreme, * = Chronic
Page: 19
SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
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H318 Causes serious eye damage.
H336 May cause drowsiness or dizziness.
Further information
Exposure scenario : http://www.ashland.com/file_source/Ashland/About/Document
s/R0718448_Annex_EN.pdf
Sources of key data used to compile the Safety Data Sheet
Ashland internal data including own and sponsored test reports
The UNECE administers regional agreements implementing harmonised classification for
labelling (GHS) and transport.
The information accumulated herein is believed to be accurate but is not warranted to be whether
originating with the company or not. Recipients are advised to confirm in advance of need that the
information is current, applicable, and suitable to their circumstances. This SDS has been
prepared by Ashland’s Environmental Health and Safety Department (1-800-325-3751).
Full text of other abbreviations
AICS – Australian Inventory of Chemical Substances; ASTM – American Society for the Testing of
Materials; bw – Body weight; CERCLA – Comprehensive Environmental Response,
Compensation, and Liability Act; CMR – Carcinogen, Mutagen or Reproductive Toxicant; DIN –
Standard of the German Institute for Standardisation; DOT – Department of Transportation; DSL –
Domestic Substances List (Canada); ECx – Concentration associated with x% response; EHS –
Extremely Hazardous Substance; ELx – Loading rate associated with x% response; EmS –
Emergency Schedule; ENCS – Existing and New Chemical Substances (Japan); ErCx –
Concentration associated with x% growth rate response; ERG – Emergency Response Guide;
GHS – Globally Harmonized System; GLP – Good Laboratory Practice; HMIS – Hazardous
Materials Identification System; IARC – International Agency for Research on Cancer; IATA –
International Air Transport Association; IBC – International Code for the Construction and
Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 – Half maximal inhibitory
concentration; ICAO – International Civil Aviation Organization; IECSC – Inventory of Existing
Chemical Substances in China; IMDG – International Maritime Dangerous Goods; IMO –
International Maritime Organization; ISHL – Industrial Safety and Health Law (Japan); ISO –
International Organisation for Standardization; KECI – Korea Existing Chemicals Inventory; LC50 –
Lethal Concentration to 50 % of a test population; LD50 – Lethal Dose to 50% of a test population
(Median Lethal Dose); MARPOL – International Convention for the Prevention of Pollution from
Ships; MSHA – Mine Safety and Health Administration; n.o.s. – Not Otherwise Specified; NFPA –
National Fire Protection Association; NO(A)EC – No Observed (Adverse) Effect Concentration;
NO(A)EL – No Observed (Adverse) Effect Level; NOELR – No Observable Effect Loading Rate;
NTP – National Toxicology Program; NZIoC – New Zealand Inventory of Chemicals; OECD –
Organization for Economic Co-operation and Development; OPPTS – Office of Chemical Safety
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SAFETY DATA SHEET
Revision Date: 08/31/2018
Print Date: 2/26/2019
SDS Number: R0718448
BLO butyrolactone
Trademark, Ashland or its subsidiaries, registered
in various countries
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and Pollution Prevention; PBT – Persistent, Bioaccumulative and Toxic substance; PICCS –
Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR – (Quantitative) Structure
Activity Relationship; RCRA – Resource Conservation and Recovery Act; REACH – Regulation
(EC) No 1907/2006 of the European Parliament and of the Council concerning the Registration,
Evaluation, Authorisation and Restriction of Chemicals; RQ – Reportable Quantity; SADT – Self-
Accelerating Decomposition Temperature; SARA – Superfund Amendments and Reauthorization
Act; SDS – Safety Data Sheet; TCSI – Taiwan Chemical Substance Inventory; TSCA – Toxic
Substances Control Act (United States); UN – United Nations; UNRTDG – United Nations
Recommendations on the Transport of Dangerous Goods; vPvB – Very Persistent and Very
Bioaccumulative