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SAFETY DATA SHEET
PRODUCT NAME: CE 0726A DATE: June 02, 2014
SDS NUMBER: CE 0726A SUPERSEDES SDS: None
SECTION 1: MATERIAL AND MANUFACTURER IDENTIFICATION
MANUFACTURER:
Eteco, Inc.
1000 South Linwood Ave.
Santa Ana, CA 92705
Phone: 714 480 1370
TRANSPORTATION EMERGENCY CALL CHEMTREC:
800 424 9300
MEDICAL EMERGENCY INFORMATION:
800 328 8501
PRODUCT IDENTIFICATION NUMBER: CE 0726A
CHEMICAL FAMILY: POLYMERIC ISOCYANATE
SECTION 2: HAZARDOUS INGREDIENTS
MATERIAL OR COMPONENT CAS
NUMBER
% BY
WEIGH
T
POLYMERIC DIPHENYLMETHANE DIISOCYANATE 9016-87-9 100%
*Occupational Exposure Limit(s) if available, are listed in section 8.
SECTION 3: HAZARDS IDENTIFICATION
This material is classified as hazardous under OSHA Hazard Communication Standard (29 CFR 1910.1200)
Physical State and Appearance / Color: Brown Liquid. (Liquid.)
Emergency Overview: INHALATION OF MDI MISTS OR VAPORS MAY CAUSE RESPIRATORY IRRITATION,
BREATHLESSNESS, CHEST DISCOUMFORT AND REDUCED PULMONARY
FUNCTION. OVEREXPOSURE WELL ABOVE THE PEL MAY RESULT IN
BRONCHITIS, BRONCHIAL SPASMS AND PULMONARY EDEMA. LONG-TERM
EXPOSURE TO ISOCYANATES HAS BEEN REPORTED TO CAUSE LUNG DAMAGE,
INCLUDING REDUCED LUNG FUNCTION WHICH MAY BE PERMANENT. ACUTE OR
CHRONIC OVEREXPOSURE TO ISOCYANATES MAY CAUSE SENSATION IN SOME
INDIVIDUALS, RESULTING IN ALLERGIC RESPRATORY REACTIONS INCLUDING
WHEEZING, SHORTNESS OF BREATH AND DIFFICULTY BREATHING.
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Potential Acute Health Effects
Skin: HAZARDOUS IN CASE OF SKIN CONTACT (IRRITANT, SENSITIZER). SKIN INFLAMMATION IS
IS CHARACTERIZED BY ITCHING, SCALING OR REDDENING.
Eyes: HAZARDOUS IN CASE OF EYE CONTACT (IRRITANT).
Inhalation: HAZARDOUS IN CASE OF INHALATION (LUNG IRRITANT, LUNG SENSITIZER).
Ingestion: SLIGHTLY HAZARDOUS IN CASE OF INGESTION.
Medical Conditions Aggravated by Overexposure: Preexisting conditions such as asthma, allergies, eczema,
bronchitis, and other lung and skin disorders may be aggravated by exposure to the product. Results from a lifetime
inhalation study in rats indicate that MDI aerosol was carcinogenic at 9 mg/m3, the highest dose tested. This is well above
the recommended TLV of 5ppb (0.05 mg/m3). Only irritation was noted at the lower concentration of 0.2 and 1 mg/m3. No
birth defects or teratogenic effects were reported in a teratology study with rats exposed to 1, 4, and 12 mg/m3 polymeric
MDI for 6 hr/day on days 6-15 of gestation. Embryotoxicity and fetotoxicity was reported at the top dose in the presence of
maternal toxicity. As a result of previous repeated overexposures or a single large dose, certain individuals will develop
isocyanate sensitization (chemical asthma), which will cause them to react to a later exposure to isocyanate at levels well
below the PEL/TVL. Those symptoms, which include chest tightness, wheezing, cough, shortness of breath, or asthmatic
attack, could be immediate of delayed up to several hours after exposure. Similar to many non-specific asthmatic
responses, there are reports that once sensitized an individual can experience these symptoms upon exposure to dust,
cold air or other irritants. This increased lung sensitivity can persist for weeks and in severe cases for several years.
Chronic overexposure to isocyanates has also been reported to cause lung damage, including a decrease in lung
function, which may be permanent. Sensitization may e either temporary of permanent. Prolonged contact can cause
reddening, swelling, rash, scaling, or blistering, in those who have developed a skin sensitization, these symptoms can
develop as a result of contact with very small amount s of liquid material, or even as a result of vapor-only exposure.
Aggravated Medical Conditions:
Individuals who are sensitized to isocyanates and those with preexisting lung diseases of conditions, including non-
specific bronchial hyper reactivity or asthma, must avoid all exposure to isocyanates.
SECTION 4: FIRST AID MEASURES
Eyes: In case of eye contact, immediately flush eyes with running water for at least 15 minutes, keeping the
eyelids open. Get immediate medical attention.
Skin Contact: Remove contaminated clothing. In case of contact, immediately wash skin with soap and plenty of water.
If symptoms develop obtain medical attention. Contaminated clothing should be thoroughly cleaned. An
MDI study has demonstrated that a polyglycol-based skin cleaner or corn oil may be more effective than
soap and water.
Inhalation: If excessive inhalation of vapor occurs, remove patient to fresh air. If not breathing, give artificial
respiration, preferably mouth-to-mouth. If breathing is difficult, qualified personnel may administer
oxygen. Get immediate medical attention.
Ingestion: If swallowed, dilute with water. DO NOT INDUCE VOMITING. Never give fluids or induce vomiting if the
victim is unconscious or having convulsions. Get immediate medical attention.
NOTES TO PHYSICIANS: There is no specific antidote to counteract the effects of MDI. Symptomatic and
supportive therapy as needed. Following severe exposure medical follow-up should be
monitored for at least 48 hours.
Other First Aid Procedures: Medical supervision of all employees who handle or come into contact with MDI is
recommended. Pre-employment and periodic medical examinations with respiratory
function test (PEV, PVC, as a minimum are suggested). Persons with asthmatic
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conditions chronic bronchitis, other chronic respiratory diseased, recurrent eczema or
pulmonary sensitization should be excluded from working with MDI. Once a person is
diagnosed as having pulmonary sensitization (allergic asthma) to MDI, further exposure
is not permissible.
SECTION 5: FIRE FIGHTING MEASURES
Flash Point: >110 C, Closed Cup.
Autoignition: >600 C.
Flammable Limits: Not available.
Products of Combustion: Carbon Monoxide, Carbon Dioxide, Nitrous Oxide and HCN.
Fire-fighting media and SMALL FIRE: Use DRY chemical powder.
instructions: LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Protective Clothing (Fire): Splash goggles. Full suit. Boots. Gloves. A self-contained breathing apparatus
should be used to avoid inhalation of the product.
Special Remarks on Fire Hazards: Reacts slowly with water to produce carbon dioxide which may rupture closed
containers. This reaction accelerates at higher temperatures.
SECTION 6: ACCIDENTAL RELEASE MEASURES
For major spills call Chemtrec (800-424-9300)
Small Spill and Leak: Clean-up should only be performed by trained personnel. People dealing with major
spillages should wear full protective clothing including appropriate respiratory protection.
Evacuate the area. Prevent further leakage, spillage or entry into drains.
Large Spill and Leak: Contain and absorb large spillages onto an inert, non-flammable adsorbent carrier (such
as earth or sand). Shovel into open-top drums or plastic bags for further decontamination,
if necessary. Wash the spillage area with
Liquid decontaminant. Test atmosphere for MDI. Neutralize small spillages with
decontaminant. Remove and properly dispose of residues (see Section 13 for disposal
considerations). Notify applicable government authorities if release is reportable. The
CERCLA RQ for 4,4-MDI is 5000 lbs (see CERCLA in Section 15).
Decontaminant: Preparation of Decontaminant Solution: Prepare a decontamination solution of 0.2-0.5%
liquid detergent and 3-8% concentrated ammonium hydroxide in water (5-10% sodium
carbonate may be substituted for ammonium hydroxide). Follow the precautions on the
supplier s material safety data sheets when preparing and using solution.
Use of Decontamination Solution: Allow deactivated material to stand for at least 30
minutes before shoveling into drums. Do not tighten the bungs. Mixing with wet earth is
also effective, but slower.
SECTION 7: HANDLING AND STORAGE
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Handling: Avoid personal contact with the product or reaction mixture. Use only with adequate ventilation to
ensure that the occupational exposure limit is not exceeded. The efficiency of the ventilation
system must be monitored regularly because of the possibility of blockage. Avoid breathing
aerosols, mists and vapors. (See Section 8 Exposure Control for details.)
Storage: Keep containers properly sealed and when stored indoors, in a well ventilated area. Keep
contents away from moisture. Due to reaction with water, producing CO2-gas, a hazardous build-
up of pressure could result if contaminated containers are re-sealed. Do not reseal contaminated
containers. Uncontaminated containers, free of moisture, may be resealed only after placing
under a nitrogen blanket. Do not store in containers made of cooper, cooper alloys or galvanized
surfaces.
Ideal storage temperature is 16-38 C (60-100 F).
Keep stocks of decontaminant (see Section 6) readily available.
SECTION 8: EXPOSURE CONTROLS, PERSONAL PROTECTION
Preventive Measures: Conditions of use, adequacy of engineering or other control measures, and actual
exposures will dictate the need for specific protective devices at your workplace.
Engineering Controls: Use local exhaust ventilation to maintain airborne concentrations bellow the TLV.
Suitable respiratory equipment should be used in cases of insufficient ventilation or
where operational procedures demand it. For guidance on engineering control measures
refer to publications such as the ACGIH current edition of Industrial Ventilation, a
manual of Recommended Practice .
Personal Protection
Eyes: Chemical safety goggles. If there is a potential for splashing, use a full face shield.
Body and Hands: The following protective materials are recommended: Gloves-neoprene, nitrile
rubber, butyl rubber. Thin latex disposable gloves should be avoided for repeated or long term
use. Protective clothing should be selected and used in accordance with Guidelines for the
Selection of Chemical Protective Clothing published by ACGIH.
Respiratory: When the product is sprayed or heated without adequate ventilation, an approved
MSHA/NIOSH positive-pressure, supplied-air respirator may be required. Air purifying
respirators equipped with organic vapor cartridges and a HEPA (P100) particulate filter
may be used under certain conditions when a cartridge change-out schedule has been
developed in accordance with the OSHA respiratory protection standard (29 C.F.R.
1910.134).
Personal Protection in Case of a Large Spills: Splash goggles. Full suit. Vapor respirator or a self-contained
breathing apparatus. Boots. Gloves. Suggested protective
clothing might not be sufficient; consult a specialist BEFORE
handling this product.
Product Name Exposure Limits
4,4-Diphenylmethane Diisocyanate ACGIH TLV 0.05 mg/m3 (8-hour, 40 hours/week)
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OSHA PEL Ceiling Limit 0.20 mg/m3
NIOSH REL/TWA 0.05 mg/m3 (10-hour, 40 hours/week)
NIOSH REL/CEILING 0.20 mg/m3 (10-minutes)
Exposure control/ personal protection: Medical supervision of all employees who handle or come in contact with
respiratory sensitizers is recommended. Persons with respiratory
problems including asthmatic-type conditions, chronic
Bronchitis, other chronic respiratory diseases or recurrent skin eczema
or skin allergies should be evaluated for their suitability of working with
this product. Once a person is diagnosed as sensitized, no further
exposure to the material that caused the sensitization should be
permitted. The Occupational Exposure limits do not apply to previously
sensitized individuals.
SECTION 9: PHYSICAL AHD CHEMICAL PROPERTIES
APPEARANCE AND ODOR Brown Liquid Slightly Musty
BOILING POINT ( C) >300 C
MELTING POINT ( F/ C) Not available
SPECIFIC GRAVITY ( WATER = 1) 1.03 gr/ml
BULK DENSITY 8.6 lb/gal
pH Not applicable
VAPOR PRESSURE (MM Hg.) 0.000004 mmHg @ 25 C
VAPOR DENSITY (AIR-1) 8.5
VISCOSITY 200-300 cps @ 25 C
PERCENT (%) VOC 0%
FLASH POINTS >110 C (230 F) Closed Cup
SECTION 10: STABILITY AND REACTIVITY
Stability: Stable at room temperature.
Incompatibility with
various Substances: Reactive with moisture.
Conditions of Instability: Avoid high temperatures. Avoid freezing.
Hazardous Decomposition
Products: Carbon Monoxide, Carbon Dioxide, Nitrous Oxide and HCN.
Hazardous Polymerization: Polymerization may occur at elevated temperatures in the presence of alkalies, tertiary
amines and metal compounds.
SECTION 11: TOXICOLOGICAL INFORMATION
Toxicity to Animals: LD50 Rat Oral: >5000mg/kg
LD50 Rabbit Dermal: >5000 mg/kg
LC50 Rat Respirable aerosol: 2240mg/m 1 hours
LC50 Rat Respirable aerosol: 490 mg/m 4 hours
Inhalation: This product is a respiratory irritant and potential respiratory sensitizer. Repeated inhalation of
vapor or aerosol at levels above the occupational exposure limit could cause respiratory
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sensitization. Symptoms may include irritation to the eyes, nose, throat and lungs, possibly
combined with dryness of the throat, tightness of chest and difficulty in breathing. The onset of
the respiratory symptoms may be delayed for several hours after exposure. A hyper-reactive
response to even minimal concentrations of MDI may develop in sensitized persons.
Skin Contact: Moderate irritant. Repeated and/or prolonged contact may cause skin sensitization. There is
limited evidence from animal studies that skin contact may play a role in respiratory sensitization.
These results emphasize the need for protective clothing including gloves to be worn at all times
when handling these chemicals or in maintenance work.
Eye Contact: The vapor, aerosol, and liquid are irritant.
Ingestion: Ingestion may cause irritation of the gastrointestinal tract. Based on the acute oral LD50 this
product is considered practically non-toxic by ingestion.
Carcinogenic Effects: The ingredients of this product are not classified as carcinogenic by ACGIH or IARC, not
regulated as carcinogens by OSHA, and not listed as carcinogens by NTP.
Mutagenic Effects: There is no substantial evidence of mutagenic potential.
Reproductive Effects: No adverse reproductive effects are anticipated.
Teratogenic Effects: No birth defects were seen in two independent animal (rat) studies. Fetotoxicity was observed at
doses that were extremely toxic (including lethal) to the mother. Fetotoxicity was not observed at
doses that were not maternally toxic. The doses used in these studies were maximal respirable
concentrations well in excess of the defined limits.
Remark: A study was conducted where groups of rats were exposed for 6 hours/day, 5 days/week for a
lifetime to atmosphere of respirable polymeric MDI aerosol at concentrations of 0, 0.2, 1 or 6
mg/m3. No adverse effects were observed at 0.2 mg/m3. At the 1mg/m3 concentration, minimal
nasal and lung irritant effect were seen. Only at the top concentration (6.0 mg/m3) was there an
increased incidence of a benign tumor of the lung (adenoma). One malignant pulmonary tumor
(adenocarcinoma) was seen in the 6.0 mg/m3 group. MDI administration to rats in this study did
not change the distribution and incidence of tumors from those seen in control animals. The
increased incidence of lung tumors is associated with prolonged respiratory irritation and the
concurrent accumulation of yellow material in the lung. In the absence of prolonged exposure to
high concentration leading to chronic irritation and lung damage, it is highly unlikely that tumor
formation will occur.
There are reports that excessive chronic exposure to diisocyanates may result in permanent
decrease in lung function.
SECTION 12: ECOLOGICAL INFORMATION
Ecotoxicity: Polymeric MDI. LC50 (Zebra Fish) >1000 ml/l. EC50 (Daphnia magna) (24 hours) >1000 mg/l EC50 (E.
Coli) > 100ml/l.
Environmental Fate and
Distribution: It is unlikely that significant environmental exposure in the air or water will arise based on
consideration of the production and use of the substance.
Persistence and Degradation: Immiscible with water, but will react with water to produce inert and non-biodegradable
solids.
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SECTION 13: DISPOSAL CONSIDERATIONS
Waste Information: The generation of waste should be avoided or minimized wherever possible.
Disposal should be in accordance with local, state, provincial or national regulations, This
material is not hazardous waste under RCRA 40 CFR 261. Small quantities should be treated
with a decontaminant solution (see Section 6). The treated waste is not a hazardous material
under RCRA 40 CFR 261. Chemical waste, even small quantities, should never be poured down
drains, sewers or waterways.
Empty containers should be decontaminated and either passed to an approved drum recycler or
destroyed.
SECTION 14: TRANSPORT INFORMATION
For major spills call Chemtrec (800-424-9300).
DOT Classification: Single containers less than 5000 lbs. are not regulated. Single containers with 5000 lbs. Or more
of 4,4-Methylene Diphenyl Diisocyanate are regulated as: Other Regulated Substances, Liquid,
N.O.S. (Methylene Diphenyl Diisocyanate), 9, NA3082, PGlll, RQ.
TDG Classification: Not regulated.
IMO/IMDG Classification: Not regulated.
ICAO/IATA Classification: Not regulated.
SECTION 15: REGULATORY INFORMATION
U.S. Federal Regulations
This material is classified as hazardous under OSHA Hazard Communication Standard (29 CFR 1910.1200).
HCS Classification: Toxic
Irritating material
Sensitizing material
TSCA 8(b) inventory: All Ingredients Listed
EPCRA Section 313 (40 CFR 372)
Diisocyanate Compounds (Category Code N120) 98%
CERCLA (Comprehensive Environmental Response, Compensation and Liability Act):
This product does not contain nor is it manufactured with ozone depleting substances.
State Regulations: California Prop. 65: no ingredients listed.
Canadian Regulations: This material has been classified in accordance with the hazard criteria of the CPR
(Controlled Products Regulations) and this MSDS (Material Safety Data Sheet) contains
all the information required by the CPR.
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WHMIS (Canada): Class D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).
Class D-2A: Material causing other toxic effects (VERY TOXIC).
Class D-2B: Material causing other toxic effects (TOXIC).
CEPA: DSL/NDSL: All Ingredients Listed.
SECTION 16: OTHER INFORMATION
CAUSES DAMAGE TO THE FOLLOWING ORGANS: LUNGS, RESPIRATORY TRACT, SKIN
AND EYES. MAY BE HARMFULL IF INHALED. MAY CAUSE RESPIRATORY TRACT, EYE
AND SKIN IRRITATION. MAY CAUSE ALLERGIC RESPIRATORY AND SKIN REACTION.
Hazardous Material Information System (U.S.A.) National Fire Protection Association (U.S.A.)
Health: 2 Fire Hazard: 1 Reactivity: 1 Health: 2 Fire Hazard: 1 Reactivity: 1
While the information and recommendations in this publication are to the best of our knowledge, information and belief accurate at the date
of publication, NOTHING HEREIN IS TO BE CONSTRUED AS A WARRANTY, EXPRESS OR OTHERWISE.
IN ALL CASES, IT IS THE RESPONSIBILITY OF THE USER TO DETERMINE THE APPLICATION OF SUCH INFORMATION AND
RECOMMENDATIONS AND SUITABILITY OF ANY PRODUCT FOR IRS OWN PARTICULAR PURPOSE.
THE PRODUCT MAY PRESENT HAZARD AND SHOULD BE USED WITH CAUTION, WHILE CERTAIN HAZARDS ARE DESCRIBED IN THIS
PUBLICATION, NO GUARANTEE IS MADE THAT ARE THE ONLY HAZARDS THAT EXIST.
Hazards, toxicity and behavior of the products may differ when used with other materials and are dependent upon the manufacturing
circumstances or other processes. Such hazards, toxicity and behavior should be determined by the user and made known to handlers,
processors and end users.
We disclaim liability for damage or injury incurring directly or indirectly from the use of this product.
APROVED AND AUTHORIZED BY: Enes Torlic